Molecules and Mental Health

written with such clarity that readers who are not familiar with the field should have little or no difficulty understanding the material presented. Of particular current interest are the final three papers which deal with immunization against poliomyelitis. Dr. Albert Sabin presents a clear picture of present concepts of the pathogenesis of poliomyelitis (documented by careful investigation) which have led to the development of an attenuated live virus vaccine. Dr. John R. Paul et al. discuss use of Dr. Sabin's vaccine under conditions of experimental epidemiology and Dr. John P. Fox concludes with observations on the vaccine under limited field conditions. All three papers are concerned with the types of immunity conferred by natural vs. artificial means and their roles in the pathogenesis and epidemiology of the clinical disease. The entire book is timely and stimulating in providing basic facts and suggesting areas for further research. It should provide an excellent reference for students and investigators in the basic sciences and clinical research.